A new high-pressure model for the elimination of impurities from organic solvents has been added to the Ghost Trap DS* lineup.
The Ghost Trap DS* was co-developed with Daiichi Sankyo Co., Ltd. It has been designed to effectively adsorb impurities in the mobile phase in order to reduce the time required for method development and impurity analysis.
The 100 MPa pressure resistance of the Ghost Trap DS-HP allows it to be used with UHPLC systems. This permits the effective use of the Ghost Trap DS for method development by UHPLC and subsequent transfer to conventional analysis.
Consistently Traps Impurities, Even in Organic Solvents
A major feature of the Ghost Trap DS is the ability to remove impurities, even in organic solvents. When the Ghost Trap DS is installed between the gradient mixer and autosampler in reversed phase gradient analysis, it can trap impurities from the piping and gradient mixer in addition to those from the mobile phase. The example on the right shows that it can effectively trap impurities in mobile phase when the Ghost Trap DS is installed just downstream of the gradient mixer.
Application to Quantitative Analysis of Impurities Using the Nexera UHPLC
Quantitation of a small peak covered by ghost peaks can be difficult. Effective for the quantitative analysis of impurities, the Ghost Trap DS/DS-HP effectively eliminates such ghost peaks to ensure highly accurate quantitation, even with very small target component peaks.
When the Ghost Trap DS/DS-HP is not used, quantitation of an impurity peak is difficult due to the effects of ghost peaks. The Ghost Trap DS/DS-HP effectively eliminates the ghost peaks to allow quantitation of the target component.
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