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Bio Diol-300mm_1

Shim-pack Bio Diol-120, 5um, 4.6x300

Part Number: 227-31008-02

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Particle size (µm): 5

ID (mm): 4.6

Length (mm): 300

USP: L20, L33, L59

Functional Group: Diol

Mode: SEC, GFC

Type: Analytical column

Pore size (nm): 12

PH: 5 - 7.5

Pressure Tolerance (MPa): 20

Pack size: 1

Column Name: Bio Diol-120

Lead Time: 4 - 6 weeks

With different pore sizes, Shim-pack Bio Diol LC columns are effective for analysis of aggregates and fragments of mAb, oligonucleotides and carbohydrates. By reducing the particle size from 5μm to 2μm, the resolution between aggregates and monomers was greatly improved. Furthermore, by reducing the column length from 300mm to 150mm using a 2μm particle, 50% less run time was achieved, while maintaining resolution as compared to the original method that used a 5μm, 4.6 × 300mm column.

Rapid mAb Aggregate Analysis using 2μm Shim-pack Diol-300 column

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With different pore sizes, Shim-pack Bio Diol LC columns are effective for analysis of aggregates and fragments of mAb, oligonucleotides and carbohydrates. By reducing the particle size from 5μm to 2μm, the resolution between aggregates and monomers was greatly improved. Furthermore, by reducing the column length from 300mm to 150mm using a 2μm particle, 50% less run time was achieved, while maintaining resolution as compared to the original method that used a 5μm, 4.6 × 300mm column.

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