Shim-pack Scepter Claris Diol-HILIC-120, 5um, 2.1x50
Part Number: 227-31213-10
Column Name: Scepter Claris Diol-HILIC-120
Particle size (µm): 5
ID (mm): 2.1
Length (mm): 50
USP: L20
Functional Group: Diol-HILIC
Mode: HILIC
Type: Analytical column (Bioinert)
Pore size (nm): 12
End Capping: No
Carbon Load (%): 12
PH: 2 to 10
Pressure Tolerance (MPa): 45
Pack size: 1
Lead Time: 4 - 6 weeks
Shim-pack Scepter Claris features a column body with a newly-developed bioinert coating packed with Scepter series stationary phases.
- Bioinert coating is applied to the column body and stainless steel frit
- Ideal for analysis of metal-coordinating and hydrophobically adsorbing compounds such as nucleic acids, proteins, and lipids
- Outstanding pH and lifetime stability due to Scepter organic silica hybrid packing
Superior Sensitivity and Separation Performance in Nucleic Acid Analysis
Shim-pack Scepter Claris C18-120 with the bioinert coating and Scepter C18-120 with traditional stainless steel hardware were compared in this example of an analysis of a synthetic oligonucleotide. Results from Claris were highly sensitive and reproducible from the rst injection, with no loss of sample signal. Scepter C18-120 in a stainless steel column body produced low-sensitivity results and showed adsorption from the first sample injection.
Outstanding Performance in Oligonucleic Acid Analysis
Shim-pack Scepter Claris C18-120 (bioinert coating) and Scepter C18-20 (stainless steel body) were compared in this analysis of Oligodeoxythymidylic acid [d(T)20]. Results from Scepter C18-120 show low peak intensity, suggesting adsorption on metal surfaces. In contrast, Scepter Claris C18-120 produced a sharper and high-intensity peak.
Improved Sensitivity and Separation of Phospholipids
Shim-pack Scepter Claris C18-120 minimizes metal-mediated adsorption and hydrophobic absorption on the column surfaces, resulting in high-resolution separations. In this example of structurally complex phosphatidylcholine isomers, Scepter Claris C18-120 achieved increased baseline resolution between isomers with higher sensitivity.