Shim-pack Scepter


Hybrid Technology for Versatility and Superior Performance

Broad pH tolerance (pH 1 to 12*) for use with a wide range of method conditions Eight stationary phases and Three column hardware types for extensive sample coverage Scalability from analytical UHPLC to preparative purification applications

Achieve excellent stability and performance over a wide range of LC conditions with Shim-pack Scepter™- the next generation organic silica hydrid-based LC columns. Featuring different ligand functional groups, Shim-pack Scepter columns are effective for method development/scouting, and are suitable for a wide variety of applications and sample types. The three particle sizes (1.9 µm, 3 µm, 5 µm) and wide range of column dimensions make Shim-pack Scepter LC columns fully scalable between UHPLC, HPLC, and preparative LC for seamless method transfer between different laboratory instrumentation.

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Product Listing

  • Product Part
    Description:

    Shim-pack Scepter C4-300 (G), 3um, 4.0x20

    OUT OF STOCK

    Shim-pack Scepter C4-300 (G), 3um, 4.0x20

  • Product Part
    Description:

    Analytical Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31172-03

    OUT OF STOCK

    Analytical Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31172-03

  • Product Part
    Description:

    Shim-pack Scepter C4-300 (G), 5um, 2.1x20

    OUT OF STOCK

    Shim-pack Scepter C4-300 (G), 5um, 2.1x20

  • Product Part
    Description:

    Analytical Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31172-03

    OUT OF STOCK

    Analytical Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31172-03

  • Product Part
    Description:

    Shim-pack Scepter C4-300 (G), 5um, 3.0x20

    OUT OF STOCK

    Shim-pack Scepter C4-300 (G), 5um, 3.0x20

  • Product Part
    Description:

    Analytical Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31172-03

    OUT OF STOCK

    Analytical Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31172-03

  • Product Part
    Description:

    Shim-pack Scepter C4-300 (G), 5um, 4.0x20

    OUT OF STOCK

    Shim-pack Scepter C4-300 (G), 5um, 4.0x20

  • Product Part
    Description:

    Preparative Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31171-01

    OUT OF STOCK

    Preparative Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31171-01

  • Product Part
    Description:

    Preparative Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31171-02

    OUT OF STOCK

    Preparative Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31171-02

  • Product Part
    Description:

    Preparative Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31171-03

    OUT OF STOCK

    Preparative Guard Cartridge for Shim-pack Scepter C4-300, 5um Requires cartridge holder 227-31171-03

  • Product Part
    Description:

    Shim-pack Scepter (metal-free) is an inert column with a PEEK-lined stainless steel body designed for ultra-high-performance analysis. All wetted surfaces including the column body and frit are metal-free. Ideal for analysis of metal-coordinating and ion-adsorbing compounds such as phosphate-containing and basic analytes Outstanding pH and lifetime stability due to Scepter organic silica hybrid packing Shim-pack Scepter C4-300 is wide-pore organic silica hybrid reversed phase columns recommended for the separation of proteins such as monoclonal antibodies and mid-sized molecules such as oligonucleic acids and peptides that may not be retained on 100-120Å pore size columns due to size-exclusion effects. The organic silica hybrid base material is highly stable even at high temperatures under acidic and basic mobile phase conditions. Pore sizes are optimized for large molecular weight compounds and dispersed uniformly in the column, resulting in symmetrical peak shapes and increased resolution of antibodies and nucleic acids compared to a smaller pore size column. Shim-pack Scepter C4-300 is also effective for high-sensitivity LC/MS analysis, producing good peak shapes even under weak ionpairing conditions using a formic acid mobile phase. Pore Size-Dependent Selectivity Shim-pack Scepter C18-300 has larger pore sizes than Scepter C18-120, a smaller carbon content, and a lower specic surface area. As a result, Scepter C18-300 exhibits weaker retention compared to Scepter C18-120, making it suitable for applications aimed at reducing analysis time, and for the analysis of compounds that are strongly retained and may have inconsistent retention times on typical C18 columns.  

    OUT OF STOCK

    Shim-pack Scepter (metal-free) is an inert column with a PEEK-lined stainless steel body designed for ultra-high-performance analysis. All wetted surfaces including the column body and frit are metal-free. Ideal for analysis of metal-coordinating and ion-adsorbing compounds such as phosphate-containing and basic analytes Outstanding pH and lifetime stability due to Scepter organic silica hybrid packing Shim-pack Scepter C4-300 is wide-pore organic silica hybrid reversed phase columns recommended for the separation of proteins such as monoclonal antibodies and mid-sized molecules such as oligonucleic acids and peptides that may not be retained on 100-120Å pore size columns due to size-exclusion effects. The organic silica hybrid base material is highly stable even at high temperatures under acidic and basic mobile phase conditions. Pore sizes are optimized for large molecular weight compounds and dispersed uniformly in the column, resulting in symmetrical peak shapes and increased resolution of antibodies and nucleic acids compared to a smaller pore size column. Shim-pack Scepter C4-300 is also effective for high-sensitivity LC/MS analysis, producing good peak shapes even under weak ionpairing conditions using a formic acid mobile phase. Pore Size-Dependent Selectivity Shim-pack Scepter C18-300 has larger pore sizes than Scepter C18-120, a smaller carbon content, and a lower specic surface area. As a result, Scepter C18-300 exhibits weaker retention compared to Scepter C18-120, making it suitable for applications aimed at reducing analysis time, and for the analysis of compounds that are strongly retained and may have inconsistent retention times on typical C18 columns.  

  • Product Part
    Description:

    Shim-pack Scepter (metal-free) is an inert column with a PEEK-lined stainless steel body designed for ultra-high-performance analysis. All wetted surfaces including the column body and frit are metal-free. Ideal for analysis of metal-coordinating and ion-adsorbing compounds such as phosphate-containing and basic analytes Outstanding pH and lifetime stability due to Scepter organic silica hybrid packing Shim-pack Scepter C4-300 is wide-pore organic silica hybrid reversed phase columns recommended for the separation of proteins such as monoclonal antibodies and mid-sized molecules such as oligonucleic acids and peptides that may not be retained on 100-120Å pore size columns due to size-exclusion effects. The organic silica hybrid base material is highly stable even at high temperatures under acidic and basic mobile phase conditions. Pore sizes are optimized for large molecular weight compounds and dispersed uniformly in the column, resulting in symmetrical peak shapes and increased resolution of antibodies and nucleic acids compared to a smaller pore size column. Shim-pack Scepter C4-300 is also effective for high-sensitivity LC/MS analysis, producing good peak shapes even under weak ionpairing conditions using a formic acid mobile phase. Pore Size-Dependent Selectivity Shim-pack Scepter C18-300 has larger pore sizes than Scepter C18-120, a smaller carbon content, and a lower specic surface area. As a result, Scepter C18-300 exhibits weaker retention compared to Scepter C18-120, making it suitable for applications aimed at reducing analysis time, and for the analysis of compounds that are strongly retained and may have inconsistent retention times on typical C18 columns.  

    OUT OF STOCK

    Shim-pack Scepter (metal-free) is an inert column with a PEEK-lined stainless steel body designed for ultra-high-performance analysis. All wetted surfaces including the column body and frit are metal-free. Ideal for analysis of metal-coordinating and ion-adsorbing compounds such as phosphate-containing and basic analytes Outstanding pH and lifetime stability due to Scepter organic silica hybrid packing Shim-pack Scepter C4-300 is wide-pore organic silica hybrid reversed phase columns recommended for the separation of proteins such as monoclonal antibodies and mid-sized molecules such as oligonucleic acids and peptides that may not be retained on 100-120Å pore size columns due to size-exclusion effects. The organic silica hybrid base material is highly stable even at high temperatures under acidic and basic mobile phase conditions. Pore sizes are optimized for large molecular weight compounds and dispersed uniformly in the column, resulting in symmetrical peak shapes and increased resolution of antibodies and nucleic acids compared to a smaller pore size column. Shim-pack Scepter C4-300 is also effective for high-sensitivity LC/MS analysis, producing good peak shapes even under weak ionpairing conditions using a formic acid mobile phase. Pore Size-Dependent Selectivity Shim-pack Scepter C18-300 has larger pore sizes than Scepter C18-120, a smaller carbon content, and a lower specic surface area. As a result, Scepter C18-300 exhibits weaker retention compared to Scepter C18-120, making it suitable for applications aimed at reducing analysis time, and for the analysis of compounds that are strongly retained and may have inconsistent retention times on typical C18 columns.